Highly coupled transport can be achieved in free-exchange transport models
نویسندگان
چکیده
منابع مشابه
New free-exchange model of EmrE transport.
EmrE is a small multidrug resistance transporter found in Escherichia coli that confers resistance to toxic polyaromatic cations due to its proton-coupled antiport of these substrates. Here we show that EmrE breaks the rules generally deemed essential for coupled antiport. NMR spectra reveal that EmrE can simultaneously bind and cotransport proton and drug. The functional consequence of this fi...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2019
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.201912437